I used to use the FT245R chip to program my AVRs but I was looking for something more comfortable. Like the Bus Pirate. Works great. No special configuration needed for avrdude. Simply say it’s using now a Bus Pirate and which USB port it shows at.
Update: It’s too slow, so I flashed the STK500v2 firmware, which means I tell avrdude I got an STK500v2. While it loses all the features of the real Bus Pirate, it’s magnitudes faster (and I have the AVR extended patches and updated the Bus Pirate firmware to 6.1, but it was still too slow for larger programs).